ADN PHARMA - Ibutamoren MK- 677

Ibutamoren (developmental code names MK 677, MK 0677, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been shown to increase the secretion of several hormones including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels.

How it Works:

• Increasing GHRH (growth hormone releasing hormone) release.
  
  
• Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
  
  
• Reducing somatostatin release (somatostatin turns off GH release).
  
  
• Inhibiting of somatostatin receptor signaling.

Benefits

• Increased Fat Oxidation (fat loss).
  
  
• Increased Muscle gains (lean mass).
  
  
• Tightening up loose skin.
  
  
• Healing old injuries.
  
  
• Healing Bones, Tendons and Ligaments.
  In fact, many users report growing up to 6 lbs of lean muscle mass in 8 weeks of IGF-1 only cycles*. That’s an amazing result, but injecting IGF-1 daily is painful, costly and frustrating. Now, there is an oral-only alternative.

Suggested Use

 Results have been shown from doses between 5-25mgs a day, dose-dependent results should be expected. Higher doses, over 50mgs, have been reported by some but can be over doing it.

Side Effects:

 Some of the usual side effects that go with elevated GH levels such as numb hands, some lethargy, as well as slightly increased appetite have been reported with the use of Mk 677.