ADN PHARMA - Myostine YK11

YK-11 is one of the most unique compounds in the world of SARMs  although technically, it isn’t a true SARM. It’s often classified as a myostatin inhibitor with partial SARM activity, meaning it not only stimulates muscle growth by binding to androgen receptors but also limits the body’s natural ability to suppress growth through myostatin.

Myostatin is a protein that regulates muscle cell growth  in essence, it tells your body when to stop building muscle. YK-11 works by increasing follistatin, a natural antagonist to myostatin, allowing muscle cells to continue growing beyond what your body would normally permit.

The synergy between YK-11 and RAD-140 lies in their complementary mechanisms of action. While both promote muscle growth, they do so through distinct biological pathways which, when combined, can accelerate results without dramatically increasing side effects (assuming proper cycling and support).

Here’s how the synergy works:

YK-11 inhibits myostatin, a growth-limiting protein that tells your body when to stop building muscle. By boosting follistatin, YK-11 removes this natural ceiling, allowing for continued hypertrophy beyond typical physiological limits.

This mechanism makes YK-11 incredibly powerful for:

• Increasing muscle fiber size and density
  
  
• Improving muscle differentiation at the cellular level
  
  
• Gaining lean mass without significant water retention
  
  
• Producing a hard, dry look when paired with a clean diet
  
  
• YK-11 removes the growth brakes

YK-11 is also methylated (17-alpha-alkylated), which gives it excellent oral bioavailability but also means it can place some strain on the liver. Unlike most SARMs, its hybrid classification and myostatin-suppressing action put it in a league of its own.

YK-11 increases follistatin expression, which inhibits myostatin, allowing for accelerated skeletal muscle hypertrophy.

It's a compound best suited for experienced users seeking aggressive muscle growth with a relatively dry and vascular finish — especially when stacked with RAD-140.

How does it work?

The protein myostatin impairs the body’s ability to build muscle and get stronger, whereas another protein follistatin promotes muscle and strength gains. When you take YK-11 you lessen the levels of myostatin and increase those of follistatin.

Studies have shown that people with a mutation that limits myostatin production are both more muscular and stronger than those with normal amounts. YK-11 may help to inhibit the levels of myostatin in muscles by attaching to the androgen receptor.

From there, it appears to induce muscle cells to create more follistatin, which in turn limits the levels of myostatin and allows for muscle growth beyond your genetic

The synergy between YK-11 and RAD-140 lies in their complementary mechanisms of action. While both promote muscle growth, they do so through distinct biological pathways — which, when combined, can accelerate results without dramatically increasing side effects (assuming proper cycling and support).

YK-11 inhibits myostatin, a growth-limiting protein that tells your body when to stop building muscle. By boosting follistatin, YK-11 removes this natural ceiling, allowing for continued hypertrophy beyond typical physiological limits.

YK-11 Cycle

The most effective and safest YK-11 cycle appears to be between 10 and 15 mg per day taken over an 8-week cycle. However, if you are running your first YK-11 cycle, we recommend being a little more conservative with just 5 mg per day over 8 weeks.

YK-11 Dosage

The recommended dosage for running an 8-week cycle of YK-11 for mass building is between 10 and 15 mg per day, depending on your bodyweight. People under 200 pounds should take 10 mg per day, while those who weigh in excess of 200 pounds should take 15 mg per day.

If you are running your first cycle with YK-11 or taking it as part of a cutting or recomp stack, we recommend taking 5 mg per day.

YK-11 For Bodybuilding

YK-11 is an extremely popular SARM for bodybuilding as it meets every need from bulking to cutting and even recomping. Due to its ability to inhibit myostatin and encourage follistatin production, it is an extremely powerful muscle and strength booster.

Side effects

People who took YK11 and stuck to the recommended report incredible muscle and strength gain and very little side effects. Some people still report side effects such as:

• Hair-loss
  
  
• Mild acne
  
  
• Increased aggression
  
  
• Gyno 
  
  
• Lower libido